R&D Systems代理719-NG-050 Recombinant Mouse Noggin Fc Chimera Protein, CF (50 UG)-试剂-金山科研平台

R&D Systems代理719-NG-050 Recombinant Mouse Noggin Fc Chimera Protein, CF (50 UG)

2025-06-28

货号：719-NG-050

品牌：R&D Systems

规格：50ug

目录价：￥4490.00

市场价格：￥3592.00

会员价格：￥3592.00

到货时间：3~4周

金山科研平台，产品价格货期咨询微信：jinshanbio Source:Mouse myeloma cell line, NS0-derived Accession #:U79163 N-terminal Sequence Analysis:Leu20 Structure:Disulfide-linked homodimer Purity:>95%, by SDS-PAGE under reducing conditions and visualized by silver stain. Endotoxin Level: Predicted Molecular Mass:50 kDa (monomer) SDS-PAGE:55-60 kDa, reducing conditions Activity:Measured by its ability to inhibit BMP-4-induced alkaline phosphatase production by ATDC5 mouse chondrogenic cells.The ED₅₀ for this effect is typically 0.06-0.3µg/mL in the presence of 75ng/mL of rhBMP-4. Formulation:Lyophilized from a 0.2 µm filtered solution in PBS.See Certificate of Analysis for details. Molecule Information: Noggin Aliases: NOG; SYM1; SYNS1 Entrez Gene IDs: 9241 (Human); 18121 (Mouse) Background: Noggin

View Noggin IHC images. Noggin was originally identified based on its dorsalizing activity in Xenopus embryos. It was subsequently found to be a BMP binding protein that antagonizes BMP bioactivities. Mammalian Noggins were subsequently identified and cloned from human, mouse, and rat cDNA libraries. Mature mouse Noggin shares 99% and 83% amino acid sequence identity with human and Xenopus Noggin, respectively. Noggin has a complex pattern of expression during embryogenesis. In the adult, Noggin is expressed in the central nervous system and in several adult peripheral tissues such as lung, skeletal muscle, and skin.

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