R&D Systems代理7194-IR-050 Recombinant Human IL-15 R alpha Fc Chimera (HEK293), CF (50 UG)-试剂-金山科研平台

R&D Systems代理7194-IR-050 Recombinant Human IL-15 R alpha Fc Chimera (HEK293), CF (50 UG)

2025-06-28

货号：7194-IR-050

品牌：R&D Systems

规格：50ug

目录价：￥4490.00

市场价格：￥3592.00

会员价格：￥3592.00

到货时间：3~4周

金山科研平台，产品价格货期咨询微信：jinshanbio Source:Human embryonic kidney cell, HEK293-derived Accession #:Q13261 N-terminal Sequence Analysis:Ile31 Structure:Disulfide-linked homodimer Purity:>95%, by SDS-PAGE under reducing conditions and visualized by silver stain. Predicted Molecular Mass:45 kDa (monomer) SDS-PAGE:75-90 kDa, reducing conditions Activity:Measured by its ability to block human IL-15-induced proliferation of CTLL‑2 mouse cytotoxic T cells. Ruchatz,H. etal. (1998) J.Immunol. 160:5654.

The ED₅₀ for this effect is typically 2 - 10 ng/mL.

Formulation:Lyophilized from a 0.2 µm filtered solution in PBS.See Certificate of Analysis for details. Molecule Information: IL-15 R alpha Long Name: Interleukin 15 Receptor alpha Aliases: CD215; IL15RA Entrez Gene IDs: 3601 (Human); 16169 (Mouse) Background: IL-15 R alpha

View IL-15 R alpha IHC images. Interleukin 15 receptor alpha (IL-15 R alpha) is a high affinity receptor that specifically binds IL-15 and associates as a heterotrimer with the IL-2 receptor beta and gamma subunits (Common gamma chain, or gamma c) to initiate signal transduction. IL-15 R alpha is expressed on a wide variety of Tand B cells as well as non-lymphoid cells. Human IL-15 R alpha shares 45% amino acid sequence homology with the mouse form of the receptor. Eight isoforms of IL-15 R alpha mRNA have been identified, resulting from alternative splicing events involving different exons.

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