金山科研平台，产品价格货期咨询微信：jinshanbio Source:Human embryonic kidney cell, HEK293-derived, Met1-Ser1383, with a C-terminal 6-His tag Accession #:NP_032539 N-terminal Sequence Analysis:Ser31 Purity:>85%, by SDS-PAGE under reducing conditions and visualized by silver stain. Predicted Molecular Mass:152.1 kDa SDS-PAGE:160 kDa, reducing conditions Activity:Measured by its binding ability in a functional ELISA.When biotinylated rhDKK-1 is immobilized at 0.25 µg/mLon a streptavidin-coated plate, recombinant mouse LRP-5 binds with an apparent K_D < 15 nM. Molecule Information: LRP-5 Long Name: LDL Receptor-related Protein 5 Aliases: BMND1; EVR1; EVR4; HBM; LRP7; OPPG; OPS; OPTA1; VBCH2 Entrez Gene IDs: 4041 (Human); 16973 (Mouse); 293649 (Rat) Background: LRP-5 LRP-5 (low-density lipoprotein receptor-related proteins -5 and -6) is a type I transmembrane protein that functions as a co-receptor with Frizzled in the canonical Wnt signaling pathway. Members of the Dickkopf (Dkk) family of proteins also interact with LRP-5, thus modulating Wnt signaling. LRP-5 polymorphisms correlate with susceptibility and resistance to osteoporosis.