金山科研平台，产品价格货期咨询微信：jinshanbio Source:Chinese Hamster Ovary cell line, CHO-derived, Gly307-Arg441 Accession #:AAA53035 N-terminal Sequence Analysis:Gly307 Purity:>95%, by SDS-PAGE under reducing conditions and visualized by silver stain. Predicted Molecular Mass:15.6 kDa SDS-PAGE:20 kDa, reducing conditions Activity:Measured by its ability to induce Smad2 phosphorylation in P19 mouse embryonal carcinoma cells. Mazerbourg, S. et al. (2004) Mol. Endocrinol. 18:653.100 ng/mL rmGDF-9 can effectively induce Smad2 phosphorylation. Molecule Information: GDF-9 Long Name: Growth Differentiation Factor 9 Entrez Gene IDs: 2661 (Human); 14566 (Mouse) Background: Growth/Differentiation Factors (GDFs) Growth/differentiation factors (GDF-1 to GDF-15) are members of the BMP family of TGF-beta superfamily proteins. They are produced as inactive preproproteins which are then cleaved and assembled into active secreted homodimers. GDF dimers are disulfide-linked with the exception of GDF-3 and -9. GDF proteins are important during embryonic development, particularly in the skeletal, nervous, and muscular systems.