金山科研平台，产品价格货期咨询微信：jinshanbio Source:Human embryonic kidney cell, HEK293-derived Accession #:NP_000034 N-terminal Sequence Analysis:Gln26 predicted: No results obtained, sequencing might be blocked Structure:Disulfide-linked homodimer Purity:>95%, by SDS-PAGE under reducing conditions and visualized by silver stain. Predicted Molecular Mass:43.2 kDa (monomer) SDS-PAGE:55-65 kDa, reducing conditions Activity:Measured by its ability to inhibit Fas Ligand-induced apoptosis of Jurkat human acute T cell leukemia cells. Cheng, J. etal. (1994) Science 263:1759.The ED₅₀ for this effect is typically6-36 ng/mL in the presence of5 ng/mL Recombinant Human FasLigand/TNFSF6 (Catalog# 126-FL). Formulation:Lyophilized from a 0.2 µm filtered solution in PBS.See Certificate of Analysis for details. Molecule Information: Fas/TNFRSF6/CD95 Long Name: Fibroblast-associated Aliases: Apo-1; APT1; CD95; TNFRSF6 Entrez Gene IDs: 355 (Human); 14102 (Mouse); 246097 (Rat); 493881 (Feline) Background: Fas/TNFRSF6 Fas (Fibroblast-associated), also known as Apo-1, CD95, and TNFRSF6, was originally identified as a cell-surface protein that binds to monoclonal antibodies that are cytolytic for various human cell lines. Alternatively spliced cDNAs encoding multiple Fas isoforms, including a soluble form of Fas, have been identified. Fas is highly expressed in epithelial cells, hepatocyes, activated mature lymphocytes, virus-transformed lymphocytes and other tumor cells. Fas expression has also been detected in mouse thymus, liver, heart, lung, kidney and ovary.