金山科研平台，产品价格货期咨询微信：jinshanbio Source:Chinese Hamster Ovary cell line, CHO-derived, Met1-Glu335 Accession #:Q01344 N-terminal Sequence Analysis:Asp21 Structure:Monomer Purity:>95%, by SDS-PAGE under reducing conditions and visualized by silver stain. Endotoxin Level: Predicted Molecular Mass:35.8 kDa SDS-PAGE:50-58 kDa, reducing conditions Activity:Measured by its ability to inhibit IL-5-dependent proliferation of TF‑1 human erythroleukemic cells. Kitamura, T. et al. (1989) J. Cell Physiol. 140:323.The ED₅₀ for this effect is typically 0.1-0.5µg/mL in the presence of 0.5 ng/mL of recombinant human IL-5. Molecule Information: IL-5 R alpha/CD125 Long Name: Interleukin 5 Receptor alpha Aliases: CD125; IL5RA Entrez Gene IDs: 3568 (Human); 16192 (Mouse) Background: IL-5 Receptor As is the case with many other cytokines, the functional high-affinity receptor for IL-5 is a complex consisting of a ligand binding subunit (alpha chain) and a second subunit (beta chain) that can modulate the ligand binding affinity of the receptor complex. In the case of IL-5, the beta subunit is shared with the high affinity receptor complexes for IL-3 and GM-CSF and is called the common beta chain.