金山科研平台，产品价格货期咨询微信：jinshanbio Source:Mouse myeloma cell line, NS0-derived Accession #:NP_001156873 N-terminal Sequence Analysis:Cys26 Structure:Disulfide-linked homodimer Purity:>95%, by SDS-PAGE under reducing conditions and visualized by silver stain. Predicted Molecular Mass:64.6 kDa (monomer) SDS-PAGE:75-80 kDa, reducing conditions Activity:Measured in a cell proliferation assay using T11 mouse plasmacytoma cells. Nordan, R.P. etal. (1987) J. Immunol. 139:813.The ED₅₀ for this effect is typically 0.5-2µg/mL in the presence of 0.75 ng/mL Recombinant Mouse IL‑11 (Catalog# 418-ML) Formulation:Lyophilized from a 0.2 µm filtered solution in PBS.See Certificate of Analysis for details. Molecule Information: IL-11 R alpha Long Name: Interleukin 11 Receptor alpha Aliases: IL11RA Entrez Gene IDs: 3590 (Human); 16157 (Mouse) Background: IL-11 R alpha Interleukin 11 receptor alpha (IL-11 R alpha) is a member of the hematopoietic cytokine receptor family that was cloned on the basis of its conserved WSXWS motif. In comparison with other hematopoietic cytokine receptors, the extracellular domain of IL-11 R alpha is closely related to that of IL-6 R alpha, CNTF R alpha and the p40 subunit of IL-12. By itself, IL-11R alpha binds IL-11 with low affinity. IL-11 R alpha, together with gp130, forms a functional high-affinity receptor complex for IL-11. The expression of IL-11 R alpha has been detected in all adult tissues examined (lung, stomach, intestine), during embryonic development and in totipotent and differentiating embryonic stem cells.