金山科研平台，产品价格货期咨询微信：jinshanbio Source:Chinese Hamster Ovary cell line, CHO-derived Accession #:AAH03874 N-terminal Sequence Analysis:Gln42 Structure:Disulfide-linked homodimer Purity:>95%, by SDS-PAGE under reducing conditions and visualized by silver stain. Predicted Molecular Mass:54 kDa (monomer) SDS-PAGE:100-150 kDa, reducing conditions Activity:Measured by the ability of the immobilized protein to support the adhesion of CHO Chinese hamster ovary cells transfected with P-Selectin.The ED₅₀ for this effect is typically 0.15-0.6 µg/mL.Optimal dilutions should be determined by each laboratory for each application. Formulation:Lyophilized from a 0.2 µm filtered solution in PBS.See Certificate of Analysis for details. Molecule Information: PSGL-1/CD162 Long Name: P-Selectin Glycoprotein Ligand 1 Aliases: CD162; SELPLG Entrez Gene IDs: 6404 (Human); 20345 (Mouse); 363930 (Rat) Background: PSGL-1 PSGL-1 (P-Selectin Glycoprotein Ligand 1) is type I transmembrane receptor found on the surface of neutrophils, monocytes, and most lymphocytes. It is expressed as a dimeric mucin-like glycoprotein that is N-glycosylated and contains both sialylated and fucosylated O-linked oligosaccharides. PSGL-1 binds to P-, E- and L-Selectins. The calcium-dependent high affinity interaction with P-, E-, and L-Selectin mediates the tethering and rolling of neutrophils, monocytes, and/or lymphocytes on endothelial cells.