R&D Systems代理7580-CL-050 Recombinant Human Collectrin Fc Chimera Protein, CF (50 UG)-试剂-金山科研平台

R&D Systems代理7580-CL-050 Recombinant Human Collectrin Fc Chimera Protein, CF (50 UG)

2025-06-28

货号：7580-CL-050

品牌：R&D Systems

规格：50ug

目录价：￥4490.00

市场价格：￥3592.00

会员价格：￥3592.00

到货时间：3~4周

金山科研平台，产品价格货期咨询微信：jinshanbio Source:Chinese Hamster Ovary cell line, CHO-derived Accession #:Q9HBJ8 N-terminal Sequence Analysis:Glu15 Structure:Disulfide-linked homodimer Purity:>95%, by SDS-PAGE under reducing conditions and visualized by silver stain. Predicted Molecular Mass:41 kDa (monomer) SDS-PAGE:54-64 kDa, reducing conditions Activity:Measured by its ability to inhibit proliferation of mIMCD‑3 mouse epithelial cells.The ED₅₀ for this effect is typically 1.0-4.0 µg/mL. Formulation:Lyophilized from a 0.2 µm filtered solution in PBS.See Certificate of Analysis for details. Molecule Information: Collectrin Aliases: NX17; TMEM27 Entrez Gene IDs: 57393 (Human); 57394 (Mouse); 57395 (Rat) Background: Collectrin

View Collectrin IHC images. Collectrin (also Transmembrane protein 27) is a 37-43 kDa member of the MEM27 family of proteins. It is expressed on pancreatic beta-cells where it regulates insulin secretion, and on renal tubular epithelium where it mediates amino acid transport. Mature mouse Collectrin is a 208 amino acid (aa) type I transmembrane glycoptotein. It contains a 127 aa extracellular region (aa 15-141) and a 60 aa cytoplasmic domain (aa 163-222). Collectrin dimerizes on the cell surface, and undergoes proteolytic cleavage to generate a 26 kDa soluble fragment. Over aa 15-144, mouse Collectrin shares 92% and 86% aa identity with rat and human Collectrin, respectively.

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