金山科研平台，产品价格货期咨询微信：jinshanbio Source:E. coli-derived, Thr6-Arg151 Accession #:P43029 N-terminal Sequence Analysis:Thr6 Structure:Disulfide-linked homodimer Purity:>95%, by SDS-PAGE under reducing conditions and visualized by silver stain. Predicted Molecular Mass:15 kDa SDS-PAGE:28 kDa, reducing conditions Activity:Measured by its ability to induce alkaline phosphatase production by ATDC5 mouse chondrogenic cells. Nakamura, K. et al. (1999) Exp. Cell Res. 250:351.The ED₅₀ for this effect is typically 0.25 - 1.25 µg/mL. Molecule Information: GDF-7/BMP-12 Long Name: Growth Differentiation Factor 7 Aliases: BMP-12 Entrez Gene IDs: 151449 (Human); 238057 (Mouse) Background: Growth/Differentiation Factors (GDFs) Growth/differentiation factors (GDF-1 to GDF-15) are members of the BMP family of TGF-beta superfamily proteins. They are produced as inactive preproproteins which are then cleaved and assembled into active secreted homodimers. GDF dimers are disulfide-linked with the exception of GDF-3 and -9. GDF proteins are important during embryonic development, particularly in the skeletal, nervous, and muscular systems.