金山科研平台，产品价格货期咨询微信：jinshanbio Source:E. coli-derived, Met1-Ser280, with a C-terminal 6-His tag Accession #:AF311388 N-terminal Sequence Analysis:Met1 Purity:>95%, by SDS-PAGE under reducing conditions and visualized by silver stain. Endotoxin Level: Predicted Molecular Mass:32 kDa SDS-PAGE:36 kDa, reducing conditions Activity:Measured by its ability to reverse the inhibition of DEVD-AFC cleavage activity in cell extracts activated by addition of cytochrome c and dATP. The IC₅₀ for this effect is typically 1.0-2.0 µM. Optimal dilutions should be determined by each laboratory for each application. Formulation:Supplied as a 0.2 µm filtered solution in HEPES, NaCl and DTT.See Certificate of Analysis for details. Molecule Information: Livin Aliases: BIRC7; KIAP; ML-IAP Entrez Gene IDs: 79444 (Human) Background: Livin Livin alpha (KIAP) and Livin beta (ML-IAP) are two splice forms generated from the livin gene. Livin is a member of the inhibitor of apoptosis protein (IAP) family that contains a baculovirus single IAP repeat (BIR) and a C-terminal RING finger domain. Livin inhibits the activation of caspases 9 and/or 3 when activated in specific cell lines. Livin alpha is a splice variant 18 amino acids longer in the BIR-RING linking region than the livin beta splice variant. The isoforms differ in their apoptotic properties.