金山科研平台，产品价格货期咨询微信：jinshanbio Source:Mouse myeloma cell line, NS0-derived, Asp268-Ser376 Accession #:O08689 N-terminal Sequence Analysis:Asp268 Structure:Disulfide-linked homodimer Purity:>90%, by SDS-PAGE with silver staining. Predicted Molecular Mass:12.4 kDa SDS-PAGE:12 kDa, reducing conditions24 kDa, non-reducing conditions Activity:Measured by its ability to induce hemoglobin expression in K562 human chronic myelogenous leukemia cells. Schwall, R.H. etal. (1991) Method Enzymol. 198:340.The ED₅₀ for this effect is typically 2-10 ng/mL. Molecule Information: GDF-8/Myostatin Long Name: Growth Differentiation Factor 8 Aliases: MSTN; Myostatin Entrez Gene IDs: 2660 (Human); 17700 (Mouse) Background: Growth/Differentiation Factors (GDFs) Growth/differentiation factors (GDF-1 to GDF-15) are members of the BMP family of TGF-beta superfamily proteins. They are produced as inactive preproproteins which are then cleaved and assembled into active secreted homodimers. GDF dimers are disulfide-linked with the exception of GDF-3 and -9. GDF proteins are important during embryonic development, particularly in the skeletal, nervous, and muscular systems.