金山科研平台，产品价格货期咨询微信：jinshanbio Source:Mouse myeloma cell line, NS0-derived Accession #:AAA60556 N-terminal Sequence Analysis:Leu32 Structure:Disulfide-linked homodimer Purity:>90%, by SDS-PAGE under reducing conditions and visualized by silver stain. Predicted Molecular Mass:37.5 kDa (monomer) SDS-PAGE:45-50 kDa, reducing conditions Activity:Measured by its binding ability in a functional ELISA.Immobilized rhActivin RIB/Fc Chimera at 2 µg/mL (100 µL/well) can bind rhCripto with a linear range of 0.8 - 100 ng/mL. Formulation:Lyophilized from a 0.2 µm filtered solution in PBS.See Certificate of Analysis for details. Molecule Information: Activin RIB/ALK-4 Long Name: Activin Receptor IB Aliases: ACVR1B; ALK-4 Entrez Gene IDs: 91 (Human); 11479 (Mouse) Background: Activin Receptors Receptors for the TGF-beta superfamily comprise two groups, the type I and the type II serine/threonine kinases. These kinases are type I transmembrane proteins, and the two subgroups are distinguished by the presence of a glycine/serine-rich juxta-membrane domain found in the type I receptors. Either a type I or type II receptor may initially bind ligand, followed by recruitment of its alternate-type receptor counterpart to generate a heteromeric signaling complex. Type I receptors are referred to as the Activin Receptor-like Kinases (ALKs), while the type II receptors are named for the ligands they bind.