R&D Systems代理811-BR-100 Recombinant Human/Mouse BMPR-II Fc Chimera Protein, CF (100 UG)-试剂-金山科研平台

R&D Systems代理811-BR-100 Recombinant Human/Mouse BMPR-II Fc Chimera Protein, CF (100 UG)

2025-06-27

货号：811-BR-100

品牌：R&D Systems

规格：100ug

目录价：￥5580.00

市场价格：￥4464.00

会员价格：￥4464.00

到货时间：3~4周

金山科研平台，产品价格货期咨询微信：jinshanbio Source:Mouse myeloma cell line, NS0-derived Accession #:Q13873 N-terminal Sequence Analysis:Met & Ser27 Structure:Disulfide-linked homodimer Purity:>97%, by SDS-PAGE under reducing conditions and visualized by silver stain. Predicted Molecular Mass:

41.5 kDa (monomer)

SDS-PAGE:65-75 kDa, reducing conditions Activity:Measured by its binding ability in a functional ELISA.

WhenRecombinant Mouse GDF-9 (Catalog# 739-G9)is immobilized at 2 µg/mL (100µL/well), theconcentration of Recombinant Human/Mouse BMPR‑II Fc Chimera that produces 50% of the optimal binding response is found to be approximately0.1‑0.5µg/mL.

Formulation:Lyophilized from a 0.2 µm filtered solution in PBS.See Certificate of Analysis for details. Molecule Information: BMPR-II Long Name: Bone Morphogenetic Protein Receptor II Aliases: BMPR2 Entrez Gene IDs: 659 (Human) Background: BMP Receptors Cellular responses to bone morphogenetic proteins (BMPs) are mediated by the formation of hetero-oligomeric complexes of type I and type II serine/threonine kinase receptors. There are seven known type I serine/threonine kinases and five mammalian type II serine/threonine kinase receptors that function in TGF-beta superfamily signal transduction. The type II receptors for TGF-beta and activin bind ligands with high affinity by themselves. In contrast, BMPR-II binding to BMP-2, BMP-4, and BMP-7 is facilitated by the presence of the type I receptor. The type I receptors are also known as activin receptor-like kinases or ALKs.

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