金山科研平台，产品价格货期咨询微信：jinshanbio Source:E. coli-derived, Met1-Asp195 Accession #:P55957 N-terminal Sequence Analysis:Met1 Purity:>95%, by SDS-PAGE under reducing conditions and visualized by silver stain. Predicted Molecular Mass:22 kDa SDS-PAGE:22 kDa, under reducing and non-reducing conditions Activity:Measured by its ability to induce cytochromec release from isolated mouse liver mitochondria.The typical EC₅₀ for cytochrome c releasing activity isless than200nM.Cytochromec is quantified using the Rat/Mouse Cytochrome c Quantikine® ELISA Kit (Catalog# MCTC0). The EC₅₀ for the desired application should be determined. Recombinant Human BID Caspase-8-cleaved is available (Catalog# 882-B8). Formulation:Supplied as a 0.2 µm filtered solution in HEPES and KCl.See Certificate of Analysis for details. Molecule Information: BID Long Name: BH3 Interacting Domain Death Agonist Entrez Gene IDs: 637 (Human); 12122 (Mouse) Background: BID (BH3 Interacting Domain Death Antagonist) BID is a member of the Bcl-2 family of proteins that regulates outer mitochondrial membrane permeability. BID is a proapoptotic member that causes Cytochrome c to be released from the mitochondrial intermembrane space into the cytosol. In healthy cells, BID is cytosolic. In response to Fas Ligand or TNF-alpha, BID is cleaved by Caspase-8 and then relocates to the mitochondrial outer membrane.