金山科研平台，产品价格货期咨询微信：jinshanbio Source:Mouse myeloma cell line, NS0-derived, Ala26-Val481 Accession #:AAD21962 N-terminal Sequence Analysis:Ala26 Purity:>97%, by SDS-PAGE under reducing conditions and visualized by silver stain. Predicted Molecular Mass:51 kDa SDS-PAGE:55- 60 kDa, reducing conditions Activity:Measured by its ability to enhance LPS-stimulated IL-8 secretion by THP‑1 human acute monocytic leukemia cells.The ED₅₀ for this effect is typically0.25-2.5ng/mL. Molecule Information: LBP Long Name: Lipopolysaccharide-binding Protein Entrez Gene IDs: 3929 (Human); 16803 (Mouse) Background: LBP Lipopolysaccharide-binding protein (LBP), a 58kDa glycoprotein synthesized in hepatocytes, belongs to a family of lipid-binding proteins that includes bactericidal/permeability increasing protein (BPI), phospholipid ester transfer protein (PLTP), and cholesterol ester transfer protein (CETP). LBP binds to the lipidA portion of lipopolysaccharide (LPS) to facilitate the process of LPS monomerization, catalyzes the binding of LPS monomers to CD14, and promotes LPS-induced immune response.