金山科研平台，产品价格货期咨询微信：jinshanbio Source:Mouse myeloma cell line, NS0-derived Accession #:Q5U0N4 N-terminal Sequence Analysis:Ala17 Structure:Disulfide-linked homodimer Purity:>95%, by SDS-PAGE under reducing conditions and visualized by silver stain. Predicted Molecular Mass:44.3 kDa (monomer) SDS-PAGE:55-65 kDa, reducing conditions Activity:Measured by its ability to inhibit BMP-4-induced activity in MC3T3‑E1 mouse preosteoblast cells.The ED₅₀ for this effect is typically 0.2 - 1 µg/mL in the presence of 50 ng/mL of rhBMP-4. Formulation:Lyophilized from a 0.2 µm filtered solution in PBS.See Certificate of Analysis for details. Molecule Information: DAN Long Name: Differential Screening-selected Gene Aberrant in Neuroblastoma Aliases: DAND1; NBL1 Entrez Gene IDs: 4681 (Human); 17965 (Mouse) Background: DAN Differential screening-selected gene aberrative in neuroblastoma (DAN) is a member of the DAN family of secreted glycoproteins that are putative BMP antagonists. There are at least five mouse DAN family members, including DAN, Gremlin/DRM, Cer1 (Cerberus-related), Dante and PRDC (protein related to DAN and cerberus). Additional DAN family members include Xenopus Cerberus, chicken Caronte, and C. elegans CeCan1.