金山科研平台，产品价格货期咨询微信：jinshanbio Source:Chinese Hamster Ovary cell line, CHO-derived, Ala197-Ile308, with an N-terminal 6-His tag Accession #:Q99988 N-terminal Sequence Analysis:His Structure:Disulfide-linked homodimer Purity:>97%, by SDS-PAGE under reducing conditions and visualized by silver stain. Endotoxin Level: Predicted Molecular Mass:13 kDa (monomer). Based on mass spectrometric analysis, a carboxyl-terminal truncated peptide with a molecular mass of approximately 12.5 kDa is also present in the recombinant protein preparation. SDS-PAGE:14 kDa, reducing conditions Activity:Bioassay data are not available.The ED₅₀ for this effect is typically 1 - 3 µg/mL in the presence of 0.1 ng/mL of rmTNF-alpha. Molecule Information: GDF-15 Long Name: Growth Differentiation Factor 15 Aliases: MIC-1; NAG-1; PDF; PLAB; PTGF-beta Entrez Gene IDs: 9518 (Human); 23886 (Mouse); 29455 (Rat) Background: Growth/Differentiation Factors (GDFs) Growth/differentiation factors (GDF-1 to GDF-15) are members of the BMP family of TGF-beta superfamily proteins. They are produced as inactive preproproteins which are then cleaved and assembled into active secreted homodimers. GDF dimers are disulfide-linked with the exception of GDF-3 and -9. GDF proteins are important during embryonic development, particularly in the skeletal, nervous, and muscular systems.