R&D Systems代理960-EP-050 Recombinant Human EpCAM/TROP1 Fc Chimera Protein, CF (50 UG)

2025-06-27

货号:960-EP-050

品牌:R&D Systems

规格:50ug

目录价:¥4490.00

市场价格:¥3592.00

会员价格:¥3592.00

  • 到货时间:3~4周

    金山科研平台,产品价格货期咨询微信:jinshanbio Source:Mouse myeloma cell line, NS0-derived Accession #:CAA32870 N-terminal Sequence Analysis:No results obtained: Gln24 predicted Structure:Disulfide-linked homodimer Purity:>90%, by SDS-PAGE under reducing conditions and visualized by silver stain. Predicted Molecular Mass:54 kDa (monomer) SDS-PAGE:60-70 kDa, reducing conditions Activity:Measured by its binding ability in a functional ELISA.The activity of this protein is measured in a homophilic binding assay.Measured by the ability of the immobilized protein to support the adhesion of the LCells mouse fibroblast cell line.

    When 5 x 104 cells/well are added to recombinant human EpCAM/Fc Chimera and human Fibronectin (0.5 µg/mL, R&D Catalog # 1918-FN) coated plates, cell adhesion is enhanced in a dose dependent manner after 45 minutes at 37°C. The ED50 for this effect is typically 0.7 - 2.8 µg/mL.

    Formulation:Lyophilized from a 0.2 µm filtered solution in PBS.See Certificate of Analysis for details. Molecule Information: EpCAM/TROP1 Long Name: Epithelial Cell Adhesion Molecule Aliases: 17-1A; CD326; GA733-2; gp40; KS1/4; M4S1; TACSTD1; TROP1 Entrez Gene IDs: 4072 (Human) Background: EpCAM/TROP-1 Epithelial Cellular Adhesion Molecule (EpCAM), also known as KS1/4, gp40, GA733-2, 17-1A, and TROP-1, is a transmembrane glycoprotein that functions as a homophilic Ca2+-independent adhesion molecule. EpCAM is expressed in fetal lung, kidney, liver, pancreas, skin, and germ cells, and in adult epithelia. EpCAM expression is elevated in human malignant neoplasia, with most carcinomas expressing EpCAM.

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