金山科研平台，产品价格货期咨询微信：jinshanbio Molecule Information: RSK1 Long Name: Ribosomal Protein S6 Kinase I Aliases: HU-1; MAPKAPL1A; RPS6KA1 Entrez Gene IDs: 6195 (Human); 20111 (Mouse); 81771 (Rat) Background: RSK (90 kDa Ribosomal Protein S6 Kinases) The 90 kDa ribosomal protein S6 kinases (RSK1-4) are a family of broadly expressed Ser/Thr kinases activated in response to mitogenic stimuli, including growth factors and tumor-promoting phorbol esters. RSKs are directly phosphorylated by ERK1 and ERK2, leading to RSK autophosphorylation and activation. Active RSKs appear to play a major role in transcriptional regulation by translocating to the nucleus and phosphorylating c-Fos and CREB.