金山科研平台，产品价格货期咨询微信：jinshanbio Molecule Information: MSK1 Long Name: Mitogen- and Stress-activated Protein Kinase 1 Aliases: RPS6KA5 Entrez Gene IDs: 9252 (Human); 73086 (Mouse) Background: MSK Mitogen- and stress-activated protein kinase 1 (MSK1), also known as ribosomal protein S6 kinase 5 (RPS6KA5), belongs to the AGC family of kinases. Both MSK1 and the related MSK2, also known as RSKB and RPS6KA4, have two kinase domains connected by a regulatory linker region, and are activated by the mitogen-activated protein kinases ERK1, ERK2, and p38. Nuclear MSK phosphorylates and activates a number of transcription factors, including ATF1 and CREB.