金山科研平台，产品价格货期咨询微信：jinshanbio Molecule Information: APE Long Name: Apurinic/Apyrimidinic Endonuclease Aliases: APEX1 Entrez Gene IDs: 328 (Human); 305605 (Rat) Background: APE Apurinic/Apyrimidinic Endonuclease (APE), also known as redox factor 1 (Ref-1), is a multifunctional enzyme involved in both DNA repair and transcription factor binding. The C-terminal region is responsible for base excision repair activities. This repair activity, however, is suppressed by phosphorylation. The N-terminal region of APE may regulate the DNA binding capabilities of a variety of transcription factors through redox stimulation.