货号：14-303M

品牌：Merck Millipore

规格：1ea

目录价：￥42566.00

市场价格：￥36181.10

会员价格：￥34052.80

金山科研平台，产品价格货期咨询微信：jinshanbio Description: MKK6/SKK3, active View All» Trade Name: Upstate (Millipore) View All» Qty/Pk: 250 µg View All» Product Overview: N-terminal, maltose binding protein tagged, human MKK6/SKK3 fusion protein, amino acids 4-end. View All» Key Applications: Kinase Assay View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Entrez Gene Summary: This gene encodes a member of the dual specificity protein kinase family, which functions as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein phosphorylates and activates p38 MAP kinase in response to inflammatory cytokines or environmental stress. As an essential component of p38 MAP kinase mediated signal transduction pathway, this gene is involved in many cellular processes such as stress induced cell cycle arrest, transcription activation and apoptosis. View All» UniProt Summary: FUNCTION: SwissProt: P52564 # Catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in MAP kinase p38 exclusively.SIZE: 334 amino acids; 37492 Da SUBUNIT: Interacts with Yersinia yopJ.TISSUE SPECIFICITY: Isoform 2 is only expressed in skeletal muscle. Isoform 1, on the other hand, is found in skeletal muscle, heart, and in lesser extent in liver or pancreas.PTM: Weakly autophosphorylated. & Acetylation of Ser-207 and Thr-211 by Yersinia yopJ prevents phosphorylation and activation, thus blocking the MAPK signaling pathway.SIMILARITY: SwissProt: P52564 ## Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase subfamily. & Contains 1 protein kinase domain. View All» Species: Human View All» Molecular Weight: 82kDa View All» Brand Family: Upstate View All» Source: Expressed in E. coli View All» Protein Target: MKK6 View All» Storage Conditions: 6 months at -70°C View All» Target Sub-Family: STE View All» Promotional Text: This enzyme is part of KinaseProfiler™, a custom inhibitor selectivity discovery service. View All» Gene Symbol:

• MAP2K6

• PRKMK6

• MEK6

• SAPKK3

• MAPKK6

• MKK6
  View All» Product Name: MKK6/SKK3, active View All» Quality Assurance: Routinely evaluated by phosphorylation of unactive p38α/SAPK2a. View All» UniProt Number: P52564 View All» Specific Activity: For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme. View All» Packaging: Also available in 10 μg size (cat#14-303) and in bulk (cat# 14-303-K). View All» Entrez Gene Number: NM_002758.3 View All» Purification Method: Amylose resin beads View All»
  © 金山科研平台是专业的授权总代理区域代理经销平台。
  © 如需询价，请加客服QQ：1749072012 、客服微信：jinshanbio，或发送邮件到1749072012@qq.com
  © 平台为生命科学研究相关领域提供一站式耗材试剂仪器解决方案和采购服务，数据资源基于CC协议。
  © 本文地址：https://www.16ao.com/thread-140336.htm
  © Merck Millipore代理14-303M MKK6/SKK3 Protein, active, 10 µg;store at -80℃，产品报价联系微信jinshanbio