货号：14-334

品牌：Merck Millipore

规格：15Ug

目录价：￥6618.00

市场价格：￥5625.30

会员价格：￥5294.40

金山科研平台，产品价格货期咨询微信：jinshanbio Description: PRAK, active View All» Trade Name: Upstate (Millipore) View All» Qty/Pk: 15 µg View All» Product Overview: N-terminal His6-tagged recombinant, human, full-length PRAK View All» Key Applications: Kinase Assay View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Entrez Gene Summary: The protein encoded by this gene is a member of the serine/threonine kinase family. In response to cellular stress and proinflammatory cytokines, this kinase is activated through its phosphorylation by MAP kinases including MAPK1/ERK, MAPK14/p38-alpha, and MAPK11/p38-beta. In vitro, this kinase phosphorylates heat shock protein HSP27 at its physiologically relevant sites. Two alternately spliced transcript variants of this gene encoding distinct isoforms have been reported. View All» UniProt Summary: FUNCTION: SwissProt: Q8IW41 # Mediates stress-induced small heat shock protein 27 phosphorylation.SIZE: 473 amino acids; 54220 Da SUBUNIT: Interacts with SQSTM1.SUBCELLULAR LOCATION: Cytoplasm (Probable). Nucleus. Note=Also observed in the nucleus.TISSUE SPECIFICITY: Expressed ubiquitously.PTM: Phosphorylated on Thr-182; which is the regulatory phosphorylation site and is located on the T-loop/loop 12.SIMILARITY: SwissProt: Q8IW41 ## Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. & Contains 1 protein kinase domain. View All» Species: Human View All» Molecular Weight: 55kDa View All» Brand Family: Upstate View All» Source: expressed by baculovirus in Sf21 insect cells View All» Protein Target: PRAK View All» Storage Conditions: 6 months at -70C View All» Target Sub-Family: CAMK View All» Promotional Text: This enzyme is part of KinaseProfiler™, a custom inhibitor selectivity discovery service. View All» Gene Symbol:

• MAPKAPK5

• PRAK
  View All» Product Name: PRAK, active View All» Quality Assurance: routinely evaluated by phosphorylation of PRAK Substrate Peptide View All» UniProt Number: Q8IW41 View All» Specific Activity: For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme. View All» Packaging: Also available in 250μg size (2x125μg) - Call for pricing and availability. Please reference catalog number 14-334M when ordering the 250μg size. View All» Entrez Gene Number:
  • NM_003668.2

  • NM_139078.1
    View All» Purification Method: Ni²⁺/NTA-agarose View All»
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    © Merck Millipore代理14-334 PRAK Protein, active, 15 µg;store at -80℃，产品报价联系微信jinshanbio