货号：14-350

品牌：Merck Millipore

规格：

目录价：￥10706.00

市场价格：￥9100.10

会员价格：￥8564.80

金山科研平台，产品价格货期咨询微信：jinshanbio Description: PTPβ View All» Trade Name: Upstate (Millipore) View All» Qty/Pk: 10000 units View All» Product Overview: GST-tagged, full-length intracellular domain of human PTPβ View All» Key Applications: Phosphatase Assay View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Entrez Gene Summary: The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and one intracytoplasmic catalytic domain, thus belongs to receptor type PTP. The extracellular region of this PTP is composed of multiple fibronectin type_III repeats, which was shown to interact with neuronal receptor and cell adhesion molecules, such as contactin and tenascin C. This protein was also found to interact with sodium channels, and thus may regulate sodium channels by altering tyrosine phosphorylation status. The functions of the interaction partners of this protein implicate the roles of this PTP in cell adhesion, neurite growth, and neuronal differentiation. Two transcript variants encoding different isoforms have been found for this gene. View All» UniProt Summary: SIZE: 1997 amino acids; 224268 Da SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein.SIMILARITY: SwissProt: P23467 ## Belongs to the protein-tyrosine phosphatase family. Receptor class 3 subfamily. & Contains 17 fibronectin type-III domains. & Contains 1 tyrosine-protein phosphatase domain. View All» Species: Human View All» Molecular Weight: 64.4kDa View All» Brand Family: Upstate View All» Source: expressed in E. coli View All» Protein Target: PTPβ View All» Storage Conditions: 6 months at -20C View All» Target Sub-Family: Tyr phosphatase View All» Gene Symbol:

• PTPRB

• R-PTP-beta

• HPTP-BETA

• PTPB

• R-PTP-BETA

• MGC59935

• HPTPB

• DKFZp686E2262

• MGC142023

• DKFZp686H15164

• FLJ44133
  View All» Product Name: PTPβ View All» Quality Assurance: routinely evaluated by dephosphorylation of p-nitrophenyl phosphate (pNPP) View All» UniProt Number: P23467 View All» Specific Activity: For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme. View All» Entrez Gene Number: NM_002837.2 View All» Purification Method: Purified from E. coli lysate using glutathioneagarose beads View All»
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