货号：14-462M

品牌：Merck Millipore

规格：1ea

目录价：￥53073.00

市场价格：￥45112.05

会员价格：￥42458.40

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Rsk3, active View All» Trade Name: Upstate (Millipore) View All» Qty/Pk: 250 µg View All» Product Overview: N-terminal His6-tagged recombinant full-length, human RSK3 View All» Key Applications: Kinase Assay View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Entrez Gene Summary: This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 non-identical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen-activated kinase (MAPK) signalling pathway. The activity of this protein has been implicated in controlling cell growth and differentiation. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. View All» UniProt Summary: FUNCTION: SwissProt: Q15349 # Serine/threonine kinase that may play a role in mediating the growth-factor and stress induced activation of the transcription factor CREB.COFACTOR: Magnesium.SIZE: 733 amino acids; 83239 Da SUBUNIT: Forms a complex with either ERK1 or ERK2 in quiescent cells. Transiently dissociates following mitogenic stimulation (By similarity).SUBCELLULAR LOCATION: Nucleus.TISSUE SPECIFICITY: Expressed in many tissues. Highest expression in lung and skeletal muscle.PTM: Autophosphorylated on Ser-377, as part of the activation process (By similarity).SIMILARITY: SwissProt: Q15349 ## Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. & Contains 1 AGC-kinase C-terminal domain. & Contains 2 protein kinase domains. View All» Species: Human View All» Molecular Weight: 87kDa View All» Brand Family: Upstate View All» Source: expressed in Sf21 insect cells View All» Protein Target: Rsk3 View All» Storage Conditions: 1 year at -70°C View All» Target Sub-Family: AGC View All» Promotional Text: This enzyme is part of KinaseProfiler™, a custom inhibitor selectivity discovery service. View All» Gene Symbol:

• RPS6KA2

• S6K-alpha

• RSK-3

• MAPKAPK1C

• RSK3

• S6K-alpha2

• pp90RSK3

• HU-2

• RSK

• p90-RSK3
  View All» Product Name: Rsk3, active View All» Quality Assurance: routinely evaluated by phosphorylation of the MAPKAP Kinase 2 substrate peptide View All» UniProt Number: Q15349 View All» Specific Activity: For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme. View All» Packaging: Also available in 10 μg size (cat#14-462) and in bulk (cat# 14-462-K). View All» Entrez Gene Number:
  • NM_001006932.1

  • NM_021135.4
    View All» Purification Method: Ni²⁺/NTA-agarose View All»
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