货号:14-479
品牌:Merck Millipore
规格:10Ug
目录价:¥6618.00
市场价格:¥5625.30
会员价格:¥5294.40
金山科研平台,产品价格货期咨询微信:jinshanbio
Description:
Rsk1/MAPKAP Kinase 1a, active
View All»
Trade Name:
Upstate (Millipore)
View All»
Qty/Pk:
10 µg
View All»
Product Overview:
Recombinant full-length rat RSK1 (residues 1-end), containing additional Nterminal His6 and HA (YPYDV PDYA) tags
View All»
Key Applications:
Kinase Assay
View All»
Usage Statement:
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
View All»
Entrez Gene Summary:
This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 nonidentical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen-activated kinase (MAPK) signalling pathway. The activity of this protein has been implicated in controlling cell growth and differentiation. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
View All»
UniProt Summary:
FUNCTION: SwissProt: Q15418 # Serine/threonine kinase that may play a role in mediating the growth-factor and stress induced activation of the transcription factor CREB.COFACTOR: Magnesium.SIZE: 735 amino acids; 82723 Da SUBUNIT: Forms a complex with either ERK1 or ERK2 in quiescent cells. Transiently dissociates following mitogenic stimulation.PTM: Autophosphorylated on Ser-380, as part of the activation process.SIMILARITY: SwissProt: Q15418 ## Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. & Contains 1 AGC-kinase C-terminal domain. & Contains 2 protein kinase domains.
View All»
Species:
Rat
View All»
Molecular Weight:
88kDa
View All»
Brand Family:
Upstate
View All»
Source:
Expressed in baculovirus in Sf21 cells
View All»
Protein Target:
Rsk1
View All»
Storage Conditions:
1 year at -70C
View All»
Target Sub-Family:
AGC
View All»
Promotional Text:
This enzyme is part of KinaseProfiler™, a custom inhibitor selectivity discovery service.
View All»
Gene Symbol:
-
RPS6KA1
-
HU-1
-
RSK-1
-
MAPKAPK1A
-
RSK
-
pp90RSK1
-
p90S6K
-
RSK1
View All»
Product Name:
Rsk1/MAPKAP Kinase 1a, active
View All»
Quality Assurance:
routinely evaluated by phosphorylation of the MAPKAP Kinase 2 substrate peptide
View All»
UniProt Number:
Q15418
View All»
Specific Activity:
For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.
View All»
Packaging:
Also available in 250 µg size --call for pricing and availability and reference catalog number 14-479M when ordering the 250 µg size.
View All»
Entrez Gene Number:
-
NM_001006665.1
-
NM_002953.3
View All»
Purification Method:
Ni2+/NTA-agarose
View All»
©
金山科研平台是专业的授权总代理区域代理经销平台。
© 如需询价,请加客服QQ:1749072012 、客服微信:jinshanbio,或发送邮件到1749072012@qq.com
© 平台为生命科学研究相关领域提供一站式耗材试剂仪器解决方案和采购服务,数据资源基于CC协议。
© 本文地址:
https://www.16ao.com/thread-140851.htm
© Merck Millipore代理14-479 Rsk1/MAPKAP Kinase 1a Protein, active, Rat, 10 µg;store at -80℃,产品报价联系微信jinshanbio
特别声明:以上内容(如有图片亦包括在内)来源于授权厂家或网络,如有侵权,请联系删除,本平台不提供信息存储服务。
Notice: The content above (including the pictures if any)comes from authorized manufacturers or networks. In case of infringement, please contact to delete it. This platform does not provide information storage services.