货号：14-506M

品牌：Merck Millipore

规格：1ea

目录价：￥47391.00

市场价格：￥40282.35

会员价格：￥37912.80

金山科研平台，产品价格货期咨询微信：jinshanbio Description: PKD2, active View All» Trade Name: Upstate (Millipore) View All» Qty/Pk: 250 µg View All» Product Overview: N-terminal His6 tagged, recombinant, full length, human PKD2 View All» Key Applications: Kinase Assay View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Entrez Gene Summary: The protein encoded by this gene belongs to the protein kinase D (PKD) family of serine/threonine protein kinases. This kinase can be activated by phorbol esters as well as by gastrin via the cholecystokinin B receptor (CCKBR) in gastric cancer cells. It can bind to diacylglycerol (DAG) in the trans-Golgi network (TGN) and may regulate basolateral membrane protein exit from TGN. Alternative splicing results in multiple transcript variants encoding different isoforms. View All» UniProt Summary: FUNCTION: SwissProt: Q9BZL6 # Calcium-independent, phospholipid-dependent, serine- and threonine-specific protein kinase.SIZE: 878 amino acids; 96722 Da TISSUE SPECIFICITY: Widely expressed.PTM: Autophosphorylated. Phorbol esters stimulates autophosphorylation. Phosphorylation of Ser-876 correlates with the activation status of the kinase.SIMILARITY: SwissProt: Q9BZL6 ## Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. & Contains 1 PH domain. & Contains 2 phorbol-ester/DAG-type zinc fingers. & Contains 1 protein kinase domain. View All» Species: Human View All» Molecular Weight: 100kDa View All» Brand Family: Upstate View All» Source: expressed in sf21 cells View All» Protein Target: PKD2 View All» Storage Conditions: 6 months at -70°C View All» Target Sub-Family: CAMK View All» Promotional Text: This enzyme is part of KinaseProfiler™, a custom inhibitor selectivity discovery service. View All» Gene Symbol:

• PRKD2

• DKFZP586E0820

• PKD2

• nPKC-D2

• HSPC187
  View All» Product Name: PKD2, active View All» Quality Assurance: routinely evaluated by phosphorylation of MAPKAP Kinase 2 Substrate Peptide View All» UniProt Number: Q9BZL6 View All» Specific Activity: For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme. View All» Packaging: Also available in 10 μg size (cat#14-506) and in bulk (cat# 14-506-K). View All» Entrez Gene Number:
  • NM_001079880.1

  • NM_001079881.1

  • NM_001079882.1

  • NM_016457.4
    View All» Purification Method: Ni²⁺/NTA-agarose View All»
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