货号:14-592M
品牌:Merck Millipore
规格:
目录价:¥39747.00
市场价格:¥33784.95
会员价格:¥31797.60
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Description:
PTPMEG-2
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Trade Name:
Upstate (Millipore)
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Qty/Pk:
250 µg
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Product Overview:
N-terminal GST-tagged, recombinant human PTP-MEG2, amino acid residues 283-end.
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Key Applications:
Phosphatase Assay
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Usage Statement:
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Entrez Gene Summary:
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an N-terminal domain that shares a significant similarity with yeast SEC14, which is a protein that has phosphatidylinositol transfer activity and is required for protein secretion through the Golgi complex in yeast. This PTP was found to be activated by polyphosphoinositide, and is thought to be involved in signaling events regulating phagocytosis.
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UniProt Summary:
FUNCTION: SwissProt: P43378 # Protein-tyrosine phosphatase that could participate in the transfer of hydrophobic ligands or in functions of the Golgi apparatus.SIZE: 593 amino acids; 68020 Da SUBCELLULAR LOCATION: Cytoplasm (Probable).SIMILARITY: SwissProt: P43378 ## Belongs to the protein-tyrosine phosphatase family. Non-receptor class 3 subfamily. & Contains 1 CRAL-TRIO domain. & Contains 1 tyrosine-protein phosphatase domain.
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Species:
Human
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Molecular Weight:
62.5kDa
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Brand Family:
Upstate
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Source:
Expressed in E. coli
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Protein Target:
PTPMEG-2
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Storage Conditions:
6 months at -70°C
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Target Sub-Family:
Tyr phosphatase
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Gene Symbol:
-
PTPN9
-
PTPase-MEG2
-
MEG2
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Product Name:
PTPMEG-2
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Quality Assurance:
Routinely evaluated by dephosphorylation of 100μM DiFMUP
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UniProt Number:
P43378
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Specific Activity:
For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme
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Packaging:
Also available in 10 μg size (cat#14-592) and in bulk (cat# 14-592-K).
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Entrez Gene Number:
NM_002833.2
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Purification Method:
Glutathione-agarose
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