货号：14-615

品牌：Merck Millipore

规格：10Ug

目录价：￥6618.00

市场价格：￥5625.30

会员价格：￥5294.40

金山科研平台，产品价格货期咨询微信：jinshanbio Description: MINK, active View All» Trade Name: Upstate (Millipore) View All» Qty/Pk: 10 µg View All» Product Overview: N-terminal His6-tagged, recombinant, human MINK amino acids 1-310 View All» Key Applications: Kinase Assay View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Entrez Gene Summary: This gene encodes a serine/threonine kinase belonging to the germinal center kinase (GCK) family. The protein is structurally similar to the kinases that are related to NIK and may belong to a distinct subfamily of NIK-related kinases within the GCK family. Studies of the mouse homolog indicate an up-regulation of expression in the course of postnatal mouse cerebral development and activation of the cJun N-terminal kinase (JNK) and the p38 pathways. Alternative splicing occurs at this locus and four transcript variants encoding distinct isoforms have been identified. View All» UniProt Summary: FUNCTION: SwissProt: Q8N4C8 # Serine/threonine kinase that may play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway. May play a role in the development of the brain (By similarity).COFACTOR: Magnesium (By similarity).SIZE: 1332 amino acids; 149810 Da TISSUE SPECIFICITY: Expressed in the brain, isoform 2 is more abundant than isoform 1.SIMILARITY: SwissProt: Q8N4C8 ## Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily. & Contains 1 CNH domain. & Contains 1 protein kinase domain. View All» Species: Human View All» Molecular Weight: 38.7kDa View All» Brand Family: Upstate View All» Source: expressed by baculovirus in Sf21 insect cells View All» Protein Target: MINK View All» Storage Conditions: 6 months at -70°C View All» Target Sub-Family: STE View All» Promotional Text: This enzyme is part of KinaseProfiler™, a custom inhibitor selectivity discovery service. View All» Gene Symbol:

• MINK1

• hMINK

• ZC3

• MINK

• MAP4K6

• B55

• hMINKbeta

• YSK2

• MGC21111
  View All» Product Name: MINK, active View All» Quality Assurance: routinely evaluated by phosphorylation of MBP View All» UniProt Number: Q8N4C8 View All» Specific Activity: For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme. View All» Entrez Gene Number:
  • NM_001024937.2

  • NM_015716.3

  • NM_153827.3

  • NM_170663.3
    View All» Purification Method: Ni²⁺/NTA-agarose View All»
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