Merck Millipore代理14-644 EPHA3, ACTIVE 10ug

2025-06-27

货号:14-644

品牌:Merck Millipore

规格:

目录价:¥4372.00

市场价格:¥3716.20

会员价格:¥3497.60

金山科研平台,产品价格货期咨询微信:jinshanbio Description: EphA3, active View All» Trade Name: Upstate (Millipore) View All» Qty/Pk: 10 µg View All» Product Overview: N-terminal 6His-tagged, recombinant, human EphA3 amino acids 578-end. View All» Key Applications: Kinase Assay View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Entrez Gene Summary: This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. This gene encodes a protein that binds ephrin-A ligands. Two alternatively spliced transcript variants have been described for this gene. View All» UniProt Summary: FUNCTION: SwissProt: P29320 # Receptor for members of the ephrin-A family. Binds to ephrin-A2, -A3, -A4 and -A5. Could play a role in lymphoid function.SIZE: 983 amino acids; 110131 Da SUBCELLULAR LOCATION: Isoform 1: Cell membrane; Single-pass type I membrane protein. & Isoform 2: Secreted.TISSUE SPECIFICITY: Widely expressed. Highest level in placenta.DISEASE:SwissProt: P29320 # Defects in EPHA3 may be a cause of colorectal cancer (CRC) [MIM:114500].SIMILARITY: SwissProt: P29320 ## Belongs to the protein kinase superfamily. Tyr protein kinase family. Ephrin receptor subfamily. & Contains 2 fibronectin type-III domains. & Contains 1 protein kinase domain. & Contains 1 SAM (sterile alpha motif) domain. View All» Species: Human View All» Molecular Weight: 49kDa View All» Brand Family: Upstate View All» Source: Human EphA3 amino acids 578-end, expressed by baculovirus in Sf21 insect cells. View All» Protein Target: EphA3 View All» Storage Conditions: 6 months at -70°C View All» Target Sub-Family: TK View All» Gene Symbol:

  • EPHA3

  • HEK4

  • ETK1

  • HEK

  • TYRO4

  • ETK

  • EphA3

    View All» Product Name: EphA3, active View All» Quality Assurance: routinely evaluated by phosphorylation of Poly (Glu4-Tyr) (4:1) View All» UniProt Number: P29320 View All» Specific Activity: For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme. View All» Entrez Gene Number:
    • NM_005233.3

    • NM_182644.1

      View All» Purification Method: Ni2+/NTA-agarose View All»

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