货号:14-647M
品牌:Merck Millipore
规格:
目录价:¥29267.00
市场价格:¥24876.95
会员价格:¥23413.60
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Description:
SGK3, active
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Trade Name:
Upstate (Millipore)
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Qty/Pk:
250 µg
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Product Overview:
N-terminal 6His-tagged, recombinant, human SGK3 amino acids 119-end
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Key Applications:
Kinase Assay
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Usage Statement:
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Entrez Gene Summary:
This gene is a member of the Ser/Thr protein kinase family and encodes a phosphoprotein with a PX (phox homology) domain. The protein phosphorylates several target proteins and has a role in neutral amino acid transport and activation of potassium and chloride channels. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
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UniProt Summary:
FUNCTION: SwissProt: Q96BR1 # Involved in the activation of potassium channels. Mediates cell IL-3-dependent survival signals (By similarity).SIZE: 496 amino acids; 57108 Da SUBCELLULAR LOCATION: Cytoplasmic vesicle (By similarity). Early endosome (By similarity). Note=Localized in vesicle-like structures and in the early endosome (By similarity).TISSUE SPECIFICITY: Expressed in most tissues with highest levels in pancreas, kidney liver, heart and brain and lower levels in lung, placenta and skeletal muscle.SIMILARITY: SwissProt: Q96BR1 ## Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. & Contains 1 AGC-kinase C-terminal domain. & Contains 1 protein kinase domain. & Contains 1 PX (phox homology) domain.
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Species:
Human
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Molecular Weight:
46.7kDa
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Brand Family:
Upstate
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Source:
Expressed by baculovirus in Sf21 cells
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Protein Target:
SGK3
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Storage Conditions:
6 months at -70°C
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Target Sub-Family:
AGC
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Promotional Text:
This enzyme is part of KinaseProfiler™, a custom inhibitor selectivity discovery service.
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Gene Symbol:
-
SGK3
-
SGK2
-
CISK
-
DKFZp781N0293
-
SGKL
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Product Name:
SGK3, active
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Quality Assurance:
Routinely evaluated by phosphorylation of crosstide KK (12-555)
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UniProt Number:
Q96BR1
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Specific Activity:
For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme
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Packaging:
Also available in 10 μg size (cat#14-647) and in bulk (cat# 14-647-K).
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Entrez Gene Number:
-
NM_001033578.1
-
NM_013257.3
-
NM_170709.1
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Purification Method:
Ni2+/NTA-agarose
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