货号:14-653
品牌:Merck Millipore
规格:1ea
目录价:¥5382.00
市场价格:¥4574.70
会员价格:¥4305.60
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Description:
EphA1, active
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Trade Name:
Upstate (Millipore)
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Qty/Pk:
10 µg
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Product Overview:
N-terminal 6His-tagged, recombinant, human EphA1, amino acids 568-end.
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Key Applications:
Kinase Assay
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Usage Statement:
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Entrez Gene Summary:
This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. This gene is expressed in some human cancer cell lines and has been implicated in carcinogenesis.
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UniProt Summary:
FUNCTION: SwissProt: P21709 # Receptor for members of the ephrin-A family. Binds with a low affinity to ephrin-A1.SIZE: 976 amino acids; 108067 Da SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein.TISSUE SPECIFICITY: Overexpressed in several carcinomas.SIMILARITY: SwissProt: P21709 ## Belongs to the protein kinase superfamily. Tyr protein kinase family. Ephrin receptor subfamily. & Contains 2 fibronectin type-III domains. & Contains 1 protein kinase domain. & Contains 1 SAM (sterile alpha motif) domain.
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Species:
Human
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Molecular Weight:
50.6kDa
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Brand Family:
Upstate
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Source:
Human EphA1, amino acids 568-end, expressed by baculovirus in Sf21 insect cells.
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Protein Target:
EphA1
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Storage Conditions:
6 months at -70°C
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Target Sub-Family:
TK
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Gene Symbol:
-
EPHA1
-
EPHT
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MGC163163
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EPHT1
-
EphA1
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EPH
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Product Name:
EphA1, active
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Quality Assurance:
routinely evaluated by phosphorylation of Poly (Glu4-Tyr) (4:1)
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UniProt Number:
P21709
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Specific Activity:
For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.
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Entrez Gene Number:
NM_005232.3
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Purification Method:
Ni2+/NTA-agarose
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