金山科研平台，产品价格货期咨询微信：jinshanbio Molecule Information: MIA Long Name: Melanoma Inhibitory Activity Aliases: CD-RAP Entrez Gene IDs: 8190 (Human); 12587 (Mouse) Background: Melanoma Inhibitory Activity (MIA) MIA, also known as cartilage-derived retinoic acid-sensitive protein (CD-RAP), is a secreted protein expressed in cartilaginous tissue during development and in the adult. MIA was identified based on the fact that it is highly expressed in malignant melanomas, but not in normal melanocytes. MIA has been shown to interact with fibronectin, and promotes invasion and metastasis of melanoma cells, perhaps by blocking integrin-fibronectin interactions.