金山科研平台，产品价格货期咨询微信：jinshanbio Molecule Information: Nurr1/NGFI-B beta/NR4A2 Long Name: Nur-related Factor 1/Nerve Growth Factor Induced B beta/Nuclear Receptor Subfamily 4, Group A, 2 Aliases: NGFI-B beta; NOT; NR4A2; TINUR Entrez Gene IDs: 4929 (Human); 18227 (Mouse) Background: Nurr1 View Nurr-1 IHC images. Nurr1 belongs to the nerve growth factor-induced clone B subfamily of nuclear receptor superfamily and is designated NR4A2 in the Unified Nomenclature System for NRs. Nurr1 can function as a ligand-independent transcription factor. Nurr1 also heterodimerizes with retinoid X receptors (RXRs) to function as ligand-regulated transcription factor. Nurr 1 is important for specification of dopaminergic neurons that degenerate in Parkinson's disease. Human and mouse Nurr1 share 99% amino acid sequence homology.