金山科研平台，产品价格货期咨询微信：jinshanbio Molecule Information: FGF R4 Long Name: Fibroblast Growth Factor Receptor 4 Aliases: CD334 Entrez Gene IDs: 2264 (Human); 14186 (Mouse) Background: FGF Receptors FGF activity is mediated by a family of type I transmembrane tyrosine kinases, which undergo dimerization and autophosphorylation after ligand binding. Five distinct genes encode closely related FGF receptors, FGF R1 through 5. FGF Rs contain three Ig-like domains and a stretch of acidic residues between the first and second Ig-like domains. FGF R1, 2, 3, and -4 have a cytoplasmic split tyrosine-kinase domain, but FGF R5 does not. Multiple forms of FGF R1, 2, and 3 are generated by alternative splicing