金山科研平台，产品价格货期咨询微信：jinshanbio Molecule Information: Pentraxin 2/SAP Long Name: Serum Amyloid P Component Aliases: APCS; PTX2; SAP Entrez Gene IDs: 325 (Human); 20219 (Mouse); 29339 (Rat) Background: Pentraxin 2/SAP Pentraxin or Pentraxin 2 (PTX2), also known as Serum Amyloid P component (SAP), is a secreted serum glycoprotein belonging to the pentraxin superfamily. Pentraxins have a characteristic pentagonal discoid arrangement of five non-covalently bound subunits and bind a variety of molecules in a calcium- dependent lectin-like manner through a pattern-recognition-binding site. PTX2 is a major acute-phase protein and may function as an opsonin for a variety of ligands. PTX2 also associates ubiquitously with all amyloid deposits implicated in diseases including Alzheimer's and prion diseases, type 2 diabetes and various systemic amyloidoses.