金山科研平台，产品价格货期咨询微信：jinshanbio Molecule Information: CMG-2/ANTXR2 Long Name: Capillary Morphogenesis Protein 2 Aliases: ANTXR2; cI-35; ISH; JHS Entrez Gene IDs: 118429 (Human); 71914 (Mouse) Background: CMG-2 CMG-2 is an anthrax toxin receptor (ATR) family protein that contains one von Willebrand factor type A domain. As a result of alternative splicing, at least four isoforms of secreted or type I membrane proteins exist. CMG-2 is widely expressed in human tissues. It binds selectively to collagen type IV and laminin and is also capable of binding the protective antigen (PA) of Bacillus anthracis in a divalent cation-dependent manner. Soluble CMG-2 is a potent antitoxin and may be used as a treatment for anthrax.