金山科研平台，产品价格货期咨询微信：jinshanbio Molecule Information: SGK Long Name: Serum/Glucocorticoid Regulated Kinase 1 Entrez Gene IDs: 6446 (Human); 20393 (Mouse); 29517 (Rat) Background: SGK1 SGK1 (Serum- and glucocorticoid-regulated protein kinase 1) is a member of the AGC family of serine/threonine kinases. In addition to serum and glucocorticoids, insulin, IGF-1, osmotic shock, and mineralocorticoids have been demonstrated to activate SGK1. Normally expressed at low levels, SGK1 appears to function as a regulator of epithelial ion transport. Sustained high levels of SGK1 activation have been implicated in hypertension and diabetic nephropathy.