金山科研平台，产品价格货期咨询微信：jinshanbio Molecule Information: IFITM3/Fragilis Long Name: Interferon-induced Transmembrane Protein 3 Aliases: Fragilis; IP15; mil-1 Entrez Gene IDs: 10410 (Human); 66141 (Mouse) Background: IFITM3/Fragilis View IFITM3 IHC images. Mouse IFITM3/CD225 (also Fragilis) is a 137 amino acids (aa) 2-transmembrane protein that belongs to the Fragilis family of interferon-inducible genes. It contains two terminal extracellular domains (aa's 1 - 57 and 131 - 137) and one cytoplasmic region that potentially allows for multiple phosphorylations. The N-terminal extracellular region of mouse IFITM3 is 54%, 91% and 58% aa identical to the equivalent region in bovine, rat and human IFITM3, respectively. IFITM3 is believed to be involved in primordial germ cell clustering and regionalization.