金山科研平台，产品价格货期咨询微信：jinshanbio Molecule Information: SLAP-130 Long Name: SLP-76-associated Phosphoprotein 130 Aliases: ADAP; FYB Entrez Gene IDs: 2533 (Human); 23880 (Mouse); 499537 (Rat) Background: SLAP130 SLAP130 is a 130 kDa hematopoietic-specific adaptor protein which contains an SH3-VASP homology 1 domain. It associates with other cytoplasmic proteins such as SH2-containing Leukocyte Phosphoprotein of 76 kDa (SLP-76). SLAP130 is phosphorylated in response to TCR/CD3 stimulation, and regulates the stability of SKAP55. A SLAP130:SKAP55 signaling module stimulates beta 1 and beta 2 integrin activation and promotes T cell-DC cell interaction.