金山科研平台，产品价格货期咨询微信：jinshanbio Molecule Information: COX-2 Long Name: Cyclooxygenase 2 Aliases: PGHS-2; PHS-II; PTGS2 Entrez Gene IDs: 5743 (Human); 19225 (Mouse); 29527 (Rat) Background: COX Cyclooxygenase (COX), also known as prostaglandin G/H synthase, is a membrane bound enzyme partly responsible for the catalysis of prostanoid synthesis. COX is expressed as at least three different isoforms. COX-1 is constitutively expressed and thought to regulate a number of 'housekeeping' functions such as vascular hemostasis, renal blood flow, and glomerular function. COX-2 expression is tightly regulated and induced by inflammatory mediators such as growth factors, cytokines, and endotoxin. COX-3 appears to be much more strictly regulated spatially and is observed in greatest abundance in cerebral cortex.