R&D Systems代理AF4564 Human beta-Arrestin 2 Affinity Purified Polyclonal Ab (100 UG)

2025-06-27

货号:AF4564

品牌:R&D Systems

规格:100ug

目录价:¥4620.00

市场价格:¥3696.00

会员价格:¥3696.00

  • 到货时间:3~4周

    金山科研平台,产品价格货期咨询微信:jinshanbio Molecule Information: beta-Arrestin 2 Aliases: ARB2; ARR2; ARRB2 Entrez Gene IDs: 409 (Human); 216869 (Mouse); 25388 (Rat) Background: beta-Arrestin 2

    View beta-Arrestin 2 IHC images.The Arrestin family consists of four members: Arrestin 1 (visual Arrestin), Arrestin 2 (beta-Arrestin 1), Arrestin 3 (beta-Arrestin 2), and Arrestin 4 (cone Arrestin). While visual and cone Arrestins are found almost exclusively in the retina, beta-Arrestins 1 and 2 are ubiquitously expressed, and were initially described as negative regulators of G protein-coupled receptor (GPCR) signaling.

    More recently, beta-Arrestins have been determined to serve as scaffolds for various signaling pathways, including the MAPK cascades activating ERK2, p38a, and JNK3. These beta-Arrestin scaffolds tie together the appropriate kinases in series, forming a discreet signaling module that localizes components to specific subcellular environments and facilitates greater kinase activation.

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