金山科研平台，产品价格货期咨询微信：jinshanbio Molecule Information: WNK1 Long Name: WNK Lysine-deficient Protein Kinase 1 Aliases: KDP; PHA2C; PRKWNK1 Entrez Gene IDs: 65125 (Human); 232341 (Mouse); 116477 (Rat) Background: WNK1 WNK1 belongs to a novel family of serine/threonine protein kinases involved in regulating ion transport. The WNKs contain a cysteine instead of the usual lysine in their kinase activation domains. WNK1 mutations have been implicated in Pseudohypoaldosteronism type II (PHAII), an autosomal dominant disorder characterized by hypertension, increased renal salt absorption, and impaired potassium and hydrogen ion excretion.