金山科研平台，产品价格货期咨询微信：jinshanbio Molecule Information: CLEC10A/CD301 Long Name: Macrophage Galactose N-Acetyl-Galactosamine Specific Lectin 1 Aliases: CD301; CLECSF14; HML2; MGL Entrez Gene IDs: 10462 (Human) Background: CLEC10A/CD301 CLEC10A/MGL is a type II transmembrane C-type lectin that is expressed on immature myleloid dendritic cells and alternatively activated (tolerogenic) macrophages. CLEC10A/MGL binds and internalizes molecules with terminal nonsialylated GalNAc carbohydrates such as the Tn carcinoma antigen. CLEC10A/MGL also binds the GP envelope glycoprotein on Marburg and Ebola viruses and enhances viral entry and infectivity. Human and rat carry a single gene for CLEC10A/MGL, while mouse has two closely related MGL1 and MGL2 genes.