金山科研平台，产品价格货期咨询微信：jinshanbio Molecule Information: FoxC2 Long Name: Forkhead Box C2 Aliases: Fkh14; LD; MFH1 Entrez Gene IDs: 2303 (Human); 14234 (Mouse) Background: FoxC2 FoxC2 belongs to a large family of nuclear transcription factor proteins sharing a common forkhead/winged helix DNA binding domain. FoxC2 is implicated in epithelial to mesenchymal transition, human lymphedemia-distichiasis syndrome, and tumor metastasis. Experiments in mice indicate that FoxC2 controls adipocyte morphogenesis and null mice show defects in axial and cranial skeletogenesis, as well. In addition the transcriptional activity of FoxC2 influences expression of cytokine receptors such as CXCR4.