R&D Systems代理AF5065 Human/Mouse/Rat Calretinin Affinity Purified Polyclonal Ab (100 UG)-试剂-金山科研平台

R&D Systems代理AF5065 Human/Mouse/Rat Calretinin Affinity Purified Polyclonal Ab (100 UG)

2025-06-28

货号：AF5065

品牌：R&D Systems

规格：100ug

目录价：￥5040.00

市场价格：￥4032.00

会员价格：￥4032.00

到货时间：3~4周

金山科研平台，产品价格货期咨询微信：jinshanbio Molecule Information: Calretinin Aliases: CAB29; CAL2; CALB2 Entrez Gene IDs: 794 (Human); 12308 (Mouse); 117059 (Rat) Background: Calretinin

View Calretinin IHC images. Calretinin (also 29 kDa Calbindin and Calbindin 2) is a 30 kDa member of the EF-hand family of Ca²⁺-binding proteins. It serves as both an intracellular calcium sensor and calcium buffer. Calretinin is found in cerebellar granule cells plus cortical bipolar and multipolar GABAergic interneurons.

Human Calretinin is 271 amino acids (aa) in length. It contains six EF-hand domains (aa 16 - 270), each of which show a 12 aa Ca²⁺-binding motif. There are multiple splice variants. One shows a seven aa substitution for aa 181 - 190, accompanied by a 25 aa substitution for the C-terminal Met. Two others show a one and 14 aa substitution for aa 179 - 271, generating a 20 kDa and 22 kDa isoform, respectively. A fourth variant contains a seven aa substitution for aa 185 - 271. Over aa 2 - 177, human and mouse Calretinin show complete aa identity.

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