金山科研平台，产品价格货期咨询微信：jinshanbio Molecule Information: CDNF Long Name: Conserved Dopamine Neurotrophic Factor Aliases: ARMETL1 Entrez Gene IDs: 441549 (Human); 227526 (Mouse); 361276 (Rat) Background: CDNF View CDNF IHC images. CDNF (conserved dopamine neurotrophic factor), also called Armetl1 (arginine-rich, mutated in early stage tumors-like 1) in mouse, is a secreted protein that shares 62% amino acid identity with human MANF (mesencephalic-astrocyte-derived neurotrophic factor), also called Armet in mouse. Like MANF and GDNF (glial cell-derived neurotrophic factor), CDNF promotes survival of dopaminergic neurons in vitro. In a rat Parkinson's disease model, CDNF also promotes rescue and restoration of dopaminergic neurons in vivo.