金山科研平台，产品价格货期咨询微信：jinshanbio Molecule Information: Cytosolic Sulfotransferase 1E1/SULT1E1 Aliases: EST-1; STE; SULT1E1 Entrez Gene IDs: 6783 (Human); 20860 (Mouse); 25355 (Rat) Background: Cytosolic Sulfotransferase 1E1 Cytosolic Sulfotransferases catalyze the sulfation of many hormones, neurotransmitters, drugs, and xenobiotic compounds. They are distinct from Golgi resident sulfotransferases by the absence of transmembrane domains and are located in the cytoplasm. SULT1E1 is widely known as an estrogen sulfotransferase and may control estrogen levels by converting free estradiol to its inactive sulfate conjugate. Known substrates of this enzyme also include dehydroepiandrosterone, pregnenolone, ethinylestradiol, equalenin, diethylstilbesterol, 4-nitrophenol, 1-napthol and resveratrol. SULT1E1 activity is found in reproductive organs, intestine and liver.