金山科研平台，产品价格货期咨询微信：jinshanbio Molecule Information: FoxO1/FKHR Long Name: Forkhead Box O1 Aliases: FKH1; FKHR Entrez Gene IDs: 2308 (Human); 56458 (Mouse); 84482 (Rat) Background: FoxO1 FoxO1, also called FKHR (forkhead in rhabdomyosarcoma), is a ubiquitously expressed member of the forkhead box O family of winged helix transcription factors. In neurons, it is activated in response to stress, translocating to the nucleus where it promotes apoptosis and blocks proliferation. In insulin-responsive tissues, nutrient abundance triggers phosphorylation by AKT that blocks nuclear translocation and activity.